MGF (Mechano Growth Factor) - Product Overview

Category: Peptide Hormone, Growth Factor

Molecular Composition: Isoform of IGF-1 (Insulin-like Growth Factor 1) with a distinct E domain sequence.

Description:

MGF (Mechano Growth Factor) is a splice variant of IGF-1 (Insulin-like Growth Factor 1) that plays a crucial role in muscle repair and growth. Unlike the standard IGF-1, MGF is expressed in response to mechanical stress, such as resistance training or muscle injury. It is known for its potent anabolic effects, particularly in promoting muscle regeneration and enhancing muscle hypertrophy. MGF is a focus of research in fields related to muscle biology, sports science, and regenerative medicine.

Applications:

MGF is widely utilized in scientific research aimed at understanding muscle physiology, repair mechanisms, and the molecular pathways involved in muscle hypertrophy. Researchers use MGF to study its effects on muscle cell proliferation, differentiation, and its role in stimulating the repair of damaged muscle tissue. It is also investigated for its potential applications in treating muscle-wasting conditions, enhancing athletic performance, and promoting recovery from injuries.

Mechanism of Action:

MGF is produced locally in muscle tissue in response to mechanical stress or damage. It initiates muscle repair by activating satellite cells, which are muscle stem cells responsible for muscle regeneration. MGF promotes the proliferation of these cells and their differentiation into mature muscle fibers, leading to increased muscle mass and strength. This localized action makes MGF a key factor in the body’s ability to adapt to physical training and recover from muscle injuries.

Research Implications:

Research into MGF has significant implications for developing therapies to combat muscle atrophy, enhance muscle regeneration, and improve recovery from injuries. Studies often focus on its potential to boost muscle growth in individuals with muscle-wasting diseases, improve recovery times for athletes, and support rehabilitation in cases of severe muscle trauma. MGF is also explored for its broader role in regenerative medicine, where it may contribute to tissue repair and functional recovery.

Storage and Handling:

    •    Store at -20°C or lower to maintain peptide stability.

    •    Reconstitute with BAC water or a suitable buffer prior to use in experiments.

    •    Follow standard laboratory safety procedures for handling and disposal.

Note: This product is intended for research and laboratory use only. It is not intended for human or veterinary applications. All handling should comply with established laboratory protocols.