TB-500 (Thymosin Beta-4) - Product Overview

Category: Peptide, Tissue Repair and Regeneration

Molecular Composition: 43-amino acid peptide with the sequence Ser-Asp-Lys-Pro-Thr-Ser-Ile-Lys-Ile-Glu-Ile-Glu-Glu-Glu-Ile-Glu-Glu-Thr-Ile-Asp-Ala-Ile-Ser-Asp-Val-Thr-Pro-Glu-Pro-Val-Thr-Ala-Lys-Thr-Glu-Ile-Glu-Thr-Ser-Ile-Glu-Glu-Val-Lys.

Description:

TB-500, also known as Thymosin Beta-4, is a synthetic version of a naturally occurring peptide present in nearly all human and animal cells. TB-500 is primarily known for its role in promoting tissue repair, wound healing, and cell migration. It has been extensively studied for its ability to enhance recovery from injuries, reduce inflammation, and improve flexibility and strength in tissues, making it a focus of research in regenerative medicine and sports science.

Applications:

TB-500 is widely used in scientific research to explore its effects on tissue regeneration, wound healing, and the recovery process following injury. Researchers investigate its potential to accelerate the healing of tendons, ligaments, muscles, and skin. TB-500 is also studied for its role in reducing inflammation and promoting angiogenesis, which is the formation of new blood vessels. These properties make TB-500 an important peptide in studies related to sports injuries, surgical recovery, and chronic wound treatment.

Mechanism of Action:

TB-500 works by binding to actin, a protein that forms a part of the cellular cytoskeleton, and promotes cell migration, proliferation, and differentiation. It plays a significant role in the process of wound healing by increasing the production of extracellular matrix components, reducing inflammation, and enhancing tissue regeneration. TB-500’s ability to promote angiogenesis and reduce scar tissue formation contributes to its effectiveness in supporting tissue repair and recovery.

Research Implications:

Research on TB-500 has significant implications for the development of therapies aimed at improving recovery from injuries, reducing chronic inflammation, and enhancing tissue regeneration. Studies often focus on its potential to treat tendon and ligament injuries, improve post-surgical recovery, and manage chronic wounds. TB-500 is also explored for its broader applications in regenerative medicine, particularly in conditions where accelerated healing and tissue repair are desired.

Storage and Handling:

    •    Store at -20°C or lower to maintain peptide stability.

    •    Reconstitute with BAC (Bacteriostatic) water or a suitable buffer prior to use in experiments.

    •    Handle with standard laboratory safety protocols, ensuring proper disposal after use.

Note: This product is intended for research and laboratory use only. It is not intended for human or veterinary applications. All handling and usage should follow established laboratory guidelines.